NeuroGen’s unwavering distinctiveness lies in its ability to combine seamlessly, the newest developments (stem cells) with conventional, tried and tested rehabilitation techniques. The amalgamation of the new and the old in the form of synergistic teamwork, all under one roof, enables our patients to hope, in an otherwise despondent condition, for the possibility of a better quality of life.
In the past donated organs were transplanted to replace the diseased or failed organs in the recipients. Soon the number of recipients exceeded the number of donated. To overcome this demand, cell therapy offered the possibility of replacement of the damaged cells of tissue with new cells. Stem cell infusion helps to treat a plethora of conditions including cerebral palsy, spinal cord injury, intellectual disability, and other neurodegenerative syndromes as well.
Stem cells have the potential to develop into different cells of the tissues (of the body) and the ability of self-renewal. When serving as a repair system, the stem cells divide without limit as long as the person is alive. As they divide, they remain as stem cells or develop into cells with more specialized functions, like a brain cell or a muscle cell.
Stem cells, from different sources, have three common properties: They can divide and replicate themselves as long as the person is alive.
Impairments linked to neuromuscular conditions are usually irreversible due to inadequate cell regeneration or impaired cells in the central nervous system. It was observed that the cellular characteristics of autologous stem cells had the capability of treating major neurological disorders without incurring any side effects. With their neurotrophic properties, self-renewal & differentiation capacity, and immune modulation effects, the bone marrow-derived stem cells are considered as a promising candidate for treating disorders related to the nervous system.
For cell treatment, bone marrow derived mesenchymal stem cells are isolated from the marrow tissue (extracted from the patient’s hip bone) in an expedited, painless and safe way. By centrifugation procedure, a sufficient number of stem cells are separated from the unwanted tissue within a few hours. These injectable stem cells are infused intrathecally into the spinal area or the damaged muscle points, as per the need of the patients.
These bone marrow-derived stem cells have many useful properties that lead to great clinical improvement in post-cell-based therapy. According to various clinical trials, treatment with bone marrow derived mesenchymal stem cells have shown improvement in patients with traumatic brain injury, spinal cord injury and other neurological disorders through axonal sprouting and remyelination, potential to replace/protect the damaged neurons/cells, and neovascularization.
How do the infused stem cells act? Once infused into the body,
– The infused stem cells journey toward the nervous system and blend into the neural circuits to mend or improve the disrupted synaptic transmission.
– Post infusion, improved neuropathological condition, upregulated Aß clearance and reduced deposition is detected within a short period.
– The infused stem cells reduce neuroinflammation and provide protective immunomodulatory effect.
– The stem cells secrete neurotrophic influence and nerve growth factors, bringing cognitive and memory improvement in patients.
Apart from encouraging effects, renewed brain plasticity is also observed in patients following intrathecal delivery of stem cells. With the new medical breakthrough in stem cell therapy, the treatment has become a highly sought-after curative. To know about the treatment efficacy, one must understand the efficiency of stem cells in terms of engraftment, migration, cytokines and growth factors. However, cell-based therapy is a promising contribution to regenerative medicine and has gained considerable clinical attention. Read extra details on https://www.neurogenbsi.com.
Birth injuries can also affect the parts of the brain that control speech and the muscles that allow us to speak. Many children with CP have issues with speech due to their birth injury. Speech therapy can teach children how to pronounce certain words and communicate more effectively. Other senses, such as proprioception, allow people to know the location of their own body parts; being able to touch your finger to the tip of your nose is an example of the proprioceptive sense. Sensory impairments make it hard to develop movement skills, and occupational therapists help children work through these impairments. Speech therapists can diagnose speech issues and help improve language skills. They can also help with other skills, such as breathing and eating, because these issues involve the muscles in the mouth and face.
A few advices to help your child with autism: Stick to a schedule. Children with ASD tend to do best when they have a highly-structured schedule or routine. Again, this goes back to the consistency they both need and crave. Set up a schedule for your child, with regular times for meals, therapy, school, and bedtime. Try to keep disruptions to this routine to a minimum. If there is an unavoidable schedule change, prepare your child for it in advance. Reward good behavior. Positive reinforcement can go a long way with children with ASD, so make an effort to “catch them doing something good.” Praise them when they act appropriately or learn a new skill, being very specific about what behavior they’re being praised for. Also look for other ways to reward them for good behavior, such as giving them a sticker or letting them play with a favorite toy.
How can I prevent spinal cord injuries? Because spinal cord injuries are often due to unpredictable events, the best you can do is reduce your risk. Some risk-reducing measures include: always wearing a seatbelt while in a car, wearing proper protective gear while playing sports, never diving into water unless you’ve examined it first to make sure it’s deep enough and free of rocks.
Did you know that the first successful stem cell transplant took place in 1988? That year, doctors used the blood sample from the umbilical cord of a newborn to treat Fanconi’s syndrome, which his 5-year-old brother suffered from. It is estimated that more than 22,000 stem cell transplants from umbilical cord blood have been performed worldwide.
At NeuroGen, along with cell therapy there is a strong emphasis on academic work and clinical research material on stem cell therapy. A detailed analysis of the clinical data is carried out on a regular basis and this is published in various scientific journals. We have vast repertoire of stem cell publications. Currently, 95 scientific papers have been published by our team in various international and national peer reviewed medical journals. We also have 7 chapters in International textbooks and our team has also published over 18 stem cell therapy books. Read more details Stem Cell Research & Therapy.